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1

CD26, let it cut or cut it down

Ingrid De Meester, Stephan Korom, Jo Van Damme, Simon Scharpé

Journal:

Immunology Today

Year:

1999

Language:

english

File:

PDF, 273 KB

english, 1999

2

Functional Comparison of Two Human Monocyte Chemotactic Protein-2 Isoforms, Role of the Amino-Terminal Pyroglutamic Acid and Processing by CD26/Dipeptidyl Peptidase IV †

Van Coillie, Els, Proost, Paul, Van Aelst, Ilse, Struyf, Sofie, Polfliet, Machteld, De Meester, Ingrid, Harvey, David J., Van Damme, Jo, Opdenakker, Ghislain

Journal:

Year:

1998

Language:

english

File:

PDF, 251 KB

english, 1998

3

Design and Discovery of a Novel Dipeptidyl-peptidase IV (CD26)-Based Prodrug Approach

García-Aparicio, Carlos, Bonache, María-Cruz, De Meester, Ingrid, San-Félix, Ana, Balzarini, Jan, Camarasa, María-José, Velázquez, Sonsoles

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 281 KB

english, 2006

4

Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice

Jang, Jae-Hwi, Baerts, Lesley, Waumans, Yannick, De Meester, Ingrid, Yamada, Yoshito, Limani, Perparim, Gil-Bazo, Ignacio, Weder, Walter, Jungraithmayr, Wolfgang

Journal:

Clinical and Experimental Metastasis

Year:

2015

Language:

english

File:

PDF, 1.26 MB

english, 2015

5

Costimulation of CD4 + and CD8 + T cells through CD26: The ADA-binding epitope is not essential for complete signaling

De Meester, Ingrid A., Kostens, Luc L., Vanham, Guido L., Vanhoof, Greet C., Vingerhoets, Johan H., Gigase, Paul L., Scharpé, Simon L.

Journal:

Journal of Leukocyte Biology

Year:

1995

Language:

english

File:

PDF, 1.15 MB

english, 1995

6

Natural truncation of RANTES abolishes signaling through the CC chemokine receptors CCR1 and CCR3, impairs its chemotactic potency and generates a CC chemokine inhibitor

Sofie Struyf, Ingrid De Meester, Simon Scharpé, Jean-Pierre Lenaerts, Patricia Menten, Ji Ming Wang, Paul Proost, Jo Van Damme

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 217 KB

english, 1998

7

Ectopeptidases in pathophysiology

Christophe Antczak, Ingrid De Meester, Brigitte Bauvois

Journal:

Year:

2001

Language:

english

File:

PDF, 232 KB

english, 2001

8

Development of Potent and Selective Dipeptidyl Peptidase II Inhibitors.

Kristel Senten, Pieter Van der Veken, Gunther Bal, Ingrid De Meester, Anne-Marie Lambeir, Simon Scharpe, Brigitte Bauvois, Achiel Haemers, Koen Augustyns

Journal:

Year:

2003

File:

PDF, 66 KB

2003

9

Rapid Parallel Synthesis of Dipeptide Diphenyl Phosphonate Esters as Inhibitors of Dipeptidyl Peptidases.

Kristel Senten, Liesbeth Daniels, Pieter Van der Veken, Ingrid De Meester, Anne-Marie Lambeir, Simon Scharpe, Achiel Haemers, Koen Augustyns

Journal:

Year:

2003

File:

PDF, 174 KB

2003

10

Binding of adenosine deaminase to the lymphocyte surface via CD26

Ingrid De Meester, Guido Vanham, Luc Kestens, Greet Vanhoof, Eugène Bosmans, Paul Gigase, Simon Scharpé

Journal:

European Journal of Immunology

Year:

1994

Language:

english

File:

PDF, 586 KB

english, 1994

11

A new synthetic method for proline diphenyl phosphonates

Alexander Belyaev, Marianne Borloo, Koen Augustyns, Anne-Marie Lambeir, Ingrid De Meester, Simon Scharpe, Norbert Blaton, Oswald M. Peeters, Camiel De Ranter, Achiel Haemers

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 231 KB

english, 1995

12

Dipeptidyl peptidase 9 (DPP9) from bovine testes: Identification and characterization as the short form by mass spectrometry

Véronique Dubois, Anne-Marie Lambeir, Stefaan Vandamme, Veerle Matheeussen, Yves Guisez, Simon Scharpé, Ingrid De Meester

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2010

Language:

english

File:

PDF, 958 KB

english, 2010

13

Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines

Anna Soroka, Pieter Van der Veken, Ingrid De Meester, Anne-Marie Lambeir, Marie-Berthe Maes, Simon Scharpé, Achiel Haemers, Koen Augustyns

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 101 KB

english, 2006

14

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: Isoindoline containing inhibitors

Sebastiaan Van Goethem, Pieter Van der Veken, Véronique Dubois, Anna Soroka, Anne-Marie Lambeir, Xin Chen, Achiel Haemers, Simon Scharpé, Ingrid De Meester, Koen Augustyns

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 326 KB

english, 2008

15

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: Identification of dipeptide derived leads

Pieter Van der Veken, Ingrid De Meester, Véronique Dubois, Anna Soroka, Sebastiaan Van Goethem, Marie-Berthe Maes, Inger Brandt, Anne-Marie Lambeir, Xin Chen, Achiel Haemers, Simon Scharpé, Koen Augus

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 244 KB

english, 2008

16

Lower Activity of Serum Peptidases in Abstinent Alcohol-Dependent Patients

Michael Maes, Aihua Lin, Stefania Bonaccorso, Eric Vandoolaeghe, Cai Song, Filip Goossens, Ingrid De Meester, Johan Degroote, Hugo Neels, Simon Scharpé, Aleksander Janca

Journal:

Year:

1999

Language:

english

File:

PDF, 71 KB

english, 1999

17

Development of potent and selective dipeptidyl peptidase II inhibitors

Kristel Senten, Pieter Van der Veken, Gunther Bal, Ingrid De Meester, Anne-Marie Lambeir, Simon Scharpé, Brigitte Bauvois, Achiel Haemers, Koen Augustyns

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 91 KB

english, 2002

18

Molecular characterization of dipeptidyl peptidase activity in serum : Soluble CD26/dipeptidyl peptidase IV is responsible for the release of X-Pro dipeptides

Christine Durinx, Anne-Marie Lambeir, Eugène Bosmans, Jean-Bernard Falmagne, Raf Berghmans, Achiel Haemers, Simon Scharpé, Ingrid De Meester

Journal:

Year:

2000

Language:

english

File:

PDF, 400 KB

english, 2000

19

Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV

Lambeir, Anne-Marie, Durinx, Christine, Scharpé, Simon, De Meester, Ingrid

Journal:

Critical Reviews in Clinical Laboratory Sciences

Year:

2003

Language:

english

File:

PDF, 4.73 MB

english, 2003

20

Structure−Activity Relationship of Diaryl Phosphonate Esters as Potent Irreversible Dipeptidyl Peptidase IV Inhibitors

Belyaev, Alexander, Zhang, Xuemei, Augustyns, Koen, Lambeir, Anne-Marie, De Meester, Ingrid, Vedernikova, Irina, Scharpé, Simon, Haemers, Achiel

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 223 KB

english, 1999

21

Use of immobilized adenosine deaminase (EC 3.5.4.4) for the rapid purification of native human CD26/dipeptidyl peptidase IV (EC 3.4.14.5)

Ingrid De Meester, Greet Vanhoof, Anne-Marie Lambeir, Simon Scharpé

Journal:

Journal of Immunological Methods

Year:

1996

Language:

english

File:

PDF, 429 KB

english, 1996

22

Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile)

Inger Brandt, Jurgen Joossens, Xin Chen, Marie-Berthe Maes, Simon Scharpé, Ingrid De Meester, Anne-Marie Lambeir

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 342 KB

english, 2005

23

Dipeptidyl peptidase II and leukocyte cell death

Marie-Berthe Maes, Wim Martinet, Dorien M. Schrijvers, Pieter Van der Veken, Guido R.Y. De Meyer, Koen Augustyns, Anne-Marie Lambeir, Simon Scharpé, Ingrid De Meester

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 506 KB

english, 2006

24

DPP4 inhibitors for diabetes—What next?

Anne-Marie Lambeir, Simon Scharpé, Ingrid De Meester

Journal:

Biochemical Pharmacology

Year:

2008

Language:

english

File:

PDF, 174 KB

english, 2008

25

In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma

Marco M. Jost, Jens Lamerz, Harald Tammen, Christoph Menzel, Ingrid De Meester, Anne-Marie Lambeir, Koen Augustyns, Simon Scharpé, Hans Dieter Zucht, Horst Rose, Michael Jürgens, Peter Schulz-Knappe,

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 535 KB

english, 2009

26

Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP/prolyl oligopeptidase (PREP)-selectivity

Oxana Ryabtsova, Koen Jansen, Sebastiaan Van Goethem, Jurgen Joossens, Jonathan D. Cheng, Anne-Marie Lambeir, Ingrid De Meester, Koen Augustyns, Pieter Van der Veken

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 395 KB

english, 2012

27

Dipeptidyl peptidase IV (DPPIV/CD26) inhibition does not improve engraftment of unfractionated syngeneic or allogeneic bone marrow after nonmyeloablative conditioning

Elisabeth Schwaiger, Christoph Klaus, Veerle Matheeussen, Ulrike Baranyi, Nina Pilat, Haley Ramsey, Stephan Korom, Ingrid De Meester, Thomas Wekerle

Journal:

Experimental Hematology

Year:

2012

Language:

english

File:

PDF, 777 KB

english, 2012

28

Levels and profiles of PCBs and OCPs in marine benthic species from the Belgian North Sea and the Western Scheldt Estuary

Stefan Voorspoels, Adrian Covaci, Johan Maervoet, Ingrid De Meester, Paul Schepens

Journal:

Marine Pollution Bulletin

Year:

2004

Language:

english

File:

PDF, 345 KB

english, 2004

29

A kinetic study of glucagon-like peptide-1 and glucagon-like peptide-2 truncation by dipeptidyl peptidase IV, in vitro

Anne-Marie Lambeir, Paul Proost, Simon Scharpé, Ingrid De Meester

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 140 KB

english, 2002

30

CD26-processed RANTES(3–68), but not intact RANTES, has potent anti-HIV-1 activity

Dominique Schols, Paul Proost, Sofie Struyf, Anja Wuyts, Ingrid De Meester, Simon Scharpé, Jo Van Damme, Erik De Clercq

Journal:

Antiviral Research

Year:

1998

Language:

english

File:

PDF, 195 KB

english, 1998

31

A prediction of DPP IV/CD26 domain structure from a physico-chemical investigation of dipeptidyl peptidase IV (CD26) from human seminal plasma

Anne-Marie Lambeir, José Fernando Dı́az Pereira, Pablo Chacón, Geert Vermeulen, Karel Heremans, Bart Devreese, Jozef Van Beeumen, Ingrid De Meester, Simon Scharpé

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1997

Language:

english

File:

PDF, 1.00 MB

english, 1997

32

Lower serum dipeptidyl peptidase IV activity in treatment resistant major depression: Relationships with immune-inflammatory markers

Michael Maes, Ingrid De Meester, Robert Verkerk, Paul De Medts, Annick Wauters, Gertrude Vanhoof, Eric Vandoolaeghe, Hugo Neels, Simon Scharpé

Journal:

Psychoneuroendocrinology

Year:

1997

Language:

english

File:

PDF, 981 KB

english, 1997

33

EFFECTS OF PSYCHOLOGICAL STRESS ON SERUM PROLYL ENDOPEPTIDASE AND DIPEPTIDYL PEPTIDASE IV ACTIVITY IN HUMANS: HIGHER SERUM PROLYL ENDOPEPTIDASE ACTIVITY IS RELATED TO STRESS-INDUCED ANXIETY

Michael Maes, Filip Goossens, Ai-hun Lin, Ingrid De Meester, Ann Van Gastel, Simon Scharpé

Journal:

Psychoneuroendocrinology

Year:

1998

Language:

english

File:

PDF, 86 KB

english, 1998

34

The Purification, Characterization and Analysis of Primary and Secondary-Structure of Prolyl Oligopeptidase from Human Lymphocytes : Evidence that the Enzyme Belongs to the α/β Hydrolase Fold Family

Filip Goossens, Ingrid De Meester, Greet Vanhoof, Dirk Hendriks, Gert Vriend, Simon Scharpé

Journal:

Year:

1995

Language:

english

File:

PDF, 1.16 MB

english, 1995

35

Development and Evaluation of Peptide-Based Prolyl Oligopeptidase Inhibitors — Introduction of N-Benzyloxycarbonyl-Prolyl-3-Fluoropyrrolidine as a Lead in Inhibitor Design

Filip Goossens, Greet Vanhoof, Ingrid De Meester, Koen Augustyns, Marjan Borloo, Dirk Tourwe, Achiel Haemers, Simon Scharpé

Journal:

Year:

1997

Language:

english

File:

PDF, 858 KB

english, 1997

36

γ-Amino-Substituted Analogues of 1-[(S)-2,4-Diaminobutanoyl]piperidine as Highly Potent and Selective Dipeptidyl Peptidase II Inhibitors

Senten, Kristel, Van der Veken, Pieter, De Meester, Ingrid, Lambeir, Anne-Marie, Scharpé, Simon, Haemers, Achiel, Augustyns, Koen

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 208 KB

english, 2004

37

Structure–Activity Relationship Studies on Isoindoline Inhibitors of Dipeptidyl Peptidases 8 and 9 (DPP8, DPP9): Is DPP8-Selectivity an Attainable Goal?

Van Goethem, Sebastiaan, Matheeussen, Veerle, Joossens, Jurgen, Lambeir, Anne-Marie, Chen, Xin, De Meester, Ingrid, Haemers, Achiel, Augustyns, Koen, Van der Veken, Pieter

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.90 MB

english, 2011

38

Dipeptidyl Peptidase IV-Activated Prodrugs of Anti-Varicella Zoster Virus Bicyclic Nucleoside Analogues Containing Different Self-Cleavage Spacer Systems

Dr. Alberto Diez-Torrubia, Dr. Silvia Cabrera, Dr. Ingrid De Meester, Prof. María-José Camarasa, Prof. Jan Balzarini, Dr. Sonsoles Velázquez

Journal:

Year:

2012

Language:

english

File:

PDF, 799 KB

english, 2012

39

Cover Picture: Dipeptidyl Peptidase IV-Activated Prodrugs of Anti-Varicella Zoster Virus Bicyclic Nucleoside Analogues Containing Different Self-Cleavage Spacer Systems (ChemMedChem 9/2012)

Dr. Alberto Diez-Torrubia, Dr. Silvia Cabrera, Dr. Ingrid De Meester, Prof. María-José Camarasa, Prof. Jan Balzarini, Dr. Sonsoles Velázquez

Journal:

Year:

2012

Language:

english

File:

PDF, 633 KB

english, 2012

40

THE EFFECTS OF PSYCHOLOGICAL STRESS ON HUMANS: INCREASED PRODUCTION OF PRO-INFLAMMATORY CYTOKINES AND Th1-LIKE RESPONSE IN STRESS-INDUCED ANXIETY

Michael Maes, Cai Song, Aihua Lin, Raf De Jongh, An Van Gastel, Gunter Kenis, Eugene Bosmans, Ingrid De Meester, Ina Benoy, Hugo Neels, Paul Demedts, Aleksandar Janca, Simon Scharpé, Ronald S. Smith

Journal:

Year:

1998

Language:

english

File:

PDF, 156 KB

english, 1998

41

Kininase activity in human platelets: Cleavage of the Arg1-Pro2 bond of bradykinin by aminopeptidase P

Greet Vanhoof, Ingrid de Meester, Filip Goossens, Dirk Hendriks, Simon Scharpé, Arieh Yaron

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.13 MB

english, 1992

42

Exopeptidases in human platelets: an indication for proteolytic modulation of biologically active peptides

Simon L. Scharpé, Greta C. Vanhoof, Ingrid A. De Meester, Dirk F. Hendriks, Marc E. van Sande, Ludo M. Muylle, Arieh Yaron

Journal:

Clinica Chimica Acta

Year:

1991

Language:

english

File:

PDF, 461 KB

english, 1991

43

Characterization of dipeptidyl peptidase IV (CD26) from human lymphocytes

Ingrid De Meester, Greet Vanhoof, Dirk Hendriks, Hans-Ulrich Demuth, Arieh Yaron, Simon Scharpé

Journal:

Clinica Chimica Acta

Year:

1992

Language:

english

File:

PDF, 880 KB

english, 1992

44

Dipeptide-derived diphenyl phosphonate esters: mechanism-based inhibitors of dipeptidyl peptidase IV

Anne-Marie Lambeir, Marianne Borloo, Ingrid De Meester, Alexander Belyaev, Koen Augustyns, Dirk Hendriks, Simon Scharpé, Achiel Haemers

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1996

Language:

english

File:

PDF, 653 KB

english, 1996

45

Dipeptidyl peptidase II (DPPII), a review

Marie-Berthe Maes, Simon Scharpé, Ingrid De Meester

Journal:

Clinica Chimica Acta

Year:

2007

Language:

english

File:

PDF, 677 KB

english, 2007

46

Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors

Veerle Matheeussen, Anne-Marie Lambeir, Wolfgang Jungraithmayr, Nelson Gomez, Kathleen Mc Entee, Pieter Van der Veken, Simon Scharpé, Ingrid De Meester

Journal:

Clinica Chimica Acta

Year:

2012

Language:

english

File:

PDF, 364 KB

english, 2012

47

CD26/Dipeptidylpeptidase IV–targeted Therapy of Acute Lung Rejection in Rats

Florian Johannes Jung, Lin Yang, Ingrid De Meester, Koen Augustyns, Markus Cardell, Sven Hillinger, Peter Vogt, Didier Lardinois, Simon Scharpé, Walter Weder, Stephan Korom

Journal:

The Journal of Heart and Lung Transplantation

Year:

2006

Language:

english

File:

PDF, 325 KB

english, 2006

48

Intragraft DPP IV Inhibition Attenuates Post-transplant Pulmonary Ischemia/Reperfusion Injury After Extended Ischemia

Wei Zhai, Markus Cardell, Ingrid De Meester, Koen Augustyns, Sven Hillinger, Ilhan Inci, Stephan Arni, Wolfgang Jungraithmayr, Simon Scharpé, Walter Weder, Stephan Korom

Journal:

The Journal of Heart and Lung Transplantation

Year:

2007

Language:

english

File:

PDF, 608 KB

english, 2007

49

The effect of prolyl oligopeptidase inhibition on extracellular acetylcholine and dopamine levels in the rat striatum

Aaro J. Jalkanen, T. Petteri Piepponen, Jenni J. Hakkarainen, Ingrid De Meester, Anne-Marie Lambeir, Markus M. Forsberg

Journal:

Neurochemistry International

Year:

2012

Language:

english

File:

PDF, 490 KB

english, 2012

50

Search for substrates for prolyl oligopeptidase in porcine brain

Inger Brandt, Kris De Vriendt, Bart Devreese, Jozef Van Beeumen, Walter Van Dongen, Koen Augustyns, Ingrid De Meester, Simon Scharpé, Anne-Marie Lambeir

Journal:

Year:

2005

Language:

english

File:

PDF, 281 KB

english, 2005

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